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Healthcare ranking

Top 10 substance use disorder clinical trial sponsors 2026

BAT (Reynolds American) started the most substance use disorder clinical trials as lead sponsor between November 2023 and October 2026, with 13 trials. The list ranks companies worldwide by the number of new interventional trials they lead in this area.

  • Measurenew industry-sponsored clinical trials
  • PeriodNovember 2023 to October 2026
  • Ranked11 companies
  • Updated10 Nov 2026

Top 10 at a glance

  1. BAT (Reynolds American)13 trials
  2. Eli Lilly4 trials
  3. Afasci2 trials
  4. Akyso Therapeutics2 trials
  5. Clear Scientific2 trials
  6. Indivior2 trials
  7. Knoa Pharma2 trials
  8. Oregon Research Behavioral Intervention Strategies (ORBIS)2 trials
  9. Rose Research Center2 trials
  10. Tempero Bio2 trials

The full list

RankCompanyHeadquartersnew industry-sponsored clinical trials (trials)
1BAT (Reynolds American)United Kingdom13
2Eli LillyUnited States4
3AfasciUnited States2
3Akyso TherapeuticsUnited States2
3Clear ScientificUnited States2
3IndiviorUnited States2
3Knoa PharmaUnited States2
3Oregon Research Behavioral Intervention Strategies (ORBIS)United States2
3Rose Research CenterUnited States2
3Tempero BioUnited States2
3Thrive Digital HealthUnited States2

How this list is built

We counted interventional clinical trials with a company as lead sponsor and a start date from 1 November 2023 to 31 October 2026 that list substance use disorder as a studied condition; withdrawn trials are not counted. Subsidiaries and name variants are merged into the parent company, and hospitals, universities and other non-company sponsors are left out. Companies with the same count share a rank, and all companies tied at the last place are shown.

Every position is set by the data alone, by the same rules for every company. Spotted something to update? Write to info@stratummarketresearch.com with the list and the line, and we correct it within two working days.

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Frequently asked questions

Who is number one in the substance use disorder clinical trial sponsors ranking?

BAT (Reynolds American) ranks first with 13 trials (November 2023 to October 2026).

How is this ranking calculated?

We counted interventional clinical trials with a company as lead sponsor and a start date from 1 November 2023 to 31 October 2026 that list substance use disorder as a studied condition; withdrawn trials are not counted. Subsidiaries and name variants are merged into the parent company, and hospitals, universities and other non-company sponsors are left out. Companies with the same count share a rank, and all companies tied at the last place are shown.

Can a company pay to rank higher?

Positions come only from the counts described above, and inclusion is free. Every company is ranked by the same rules.

How often is the ranking updated?

Every list is recomputed each quarter from the latest public records, and the update date is printed on the page.

Can a ranked company use the badge?

Yes. Every ranked company can use the free web badge on this page on its website, in press releases and on social media.

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