+132 % change
Extra-EU imports of CN 30064000 were up 132% in 2025 compared with 2020 (€226.0 million), calculated from Eurostat values.
Eurostat1.03 EUR billion
EU exports of CN 30064000 to countries outside the EU were worth €1.03 billion in 2025.
Eurostat876.3 EUR million
Trade between EU member states in CN 30064000 (intra-EU arrivals) came to €876.3 million in 2025.
EurostatSource: Eurostat
Why this market is moving now
- Extra-EU import value moved +132% from 2020 to 2025, a direct read on EU demand for sourced supply.
- Supply is concentrated: one country provided a large share of extra-EU imports in 2025.
- US employment in the core industry shifted +9% since 2020.
What this market covers
Adhesives that bond bone fragments or fix implants, based on biological or synthetic materials. They are used in trauma, dental and craft applications, and also as animal derived glue.
Typical segments
- Surgical bone adhesives
- Cyanoacrylate bone glues
- Animal derived bone glue
- Dental bone adhesives
Who buys
- Hospitals
- Orthopedic surgeons
- Dental clinics
Largest non-EU suppliers to the EU
| Country | Import value |
|---|---|
| Liechtenstein | 216.2 EUR million |
| Japan | 115.6 EUR million |
| United States from 1995 -> 2000) | 101.4 EUR million |
| United Kingdom | 22.8 EUR million |
| Korea, Republic of | 17.0 EUR million |
| Switzerland | 16.4 EUR million |
Key figures
Each figure links to the page it came from.
| Figure | Value | Year | Source |
|---|---|---|---|
| The EU imported €524.6 million of products under CN code 30064000 (Dental cements and other dental fillings; bone reconstruction cements) from outside the EU in 2025. | 524.6 EUR million | 2025 | Eurostat |
| Extra-EU imports of CN 30064000 were up 132% in 2025 compared with 2020 (€226.0 million), calculated from Eurostat values. | +132 % change | 2025 | Eurostat |
| EU exports of CN 30064000 to countries outside the EU were worth €1.03 billion in 2025. | 1.03 EUR billion | 2025 | Eurostat |
| Trade between EU member states in CN 30064000 (intra-EU arrivals) came to €876.3 million in 2025. | 876.3 EUR million | 2025 | Eurostat |
| Liechtenstein was the largest non-EU supplier of CN 30064000 to the EU in 2025, with €216.2 million, or 41% of extra-EU imports. | 216.2 EUR million | 2025 | Eurostat |
| EU exports of CN 30064000 to the United States were €329.2 million in 2025. | 329.2 EUR million | 2025 | Eurostat |
| The average value of extra-EU imports of CN 30064000 was €416.32 per kilogram in 2025, calculated from Eurostat value and weight. | 416.32 EUR per kg | 2025 | Eurostat |
| Germany was the largest EU exporter of CN 30064000 to non-EU countries in 2025, at €516.7 million. | 516.7 EUR million | 2025 | Eurostat |
| The EU had 480 enterprises in NACE class C2052 (Manufacture of glues) in 2023. | 480 enterprises | 2023 | Eurostat |
| EU enterprises in NACE class C2052 had net turnover of €5.89 billion in 2023. | 5.89 EUR billion | 2023 | Eurostat |
| NACE class C2052 employed 15,518 people across the EU in 2023. | 15,518 persons employed | 2023 | Eurostat |
| The US had 779 private establishments in NAICS 325520 (Adhesive manufacturing) in 2025. | 779 establishments | 2025 | U.S. Bureau of Labor Statistics |
| NAICS 325520 employed an average of 24,219 people in US private industry in 2025. | 24,219 jobs | 2025 | U.S. Bureau of Labor Statistics |
| US employment in NAICS 325520 changed by +9% between 2020 (22,304 jobs) and 2025, calculated from BLS figures. | +9 % change | 2025 | U.S. Bureau of Labor Statistics |
| Average annual pay in US NAICS 325520 was $94,437 in 2025. | 94,437 USD per year | 2025 | U.S. Bureau of Labor Statistics |
| The FDA has recorded 112 510(k) clearances for devices named "bone cement". | 112 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| 17 of those clearances were issued from 2021 to 2025. | 17 510(k) clearances | 2025 | U.S. Food and Drug Administration (openFDA) |
| Depuy Orthopaedics, Inc. holds 11 510(k) clearances for devices named "bone cement". | 11 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Biomet, Inc. holds 9 510(k) clearances for devices named "bone cement". | 9 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| G21, S.R.L. holds 4 510(k) clearances for devices named "bone cement". | 4 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Medtronic holds 4 510(k) clearances for devices named "bone cement". | 4 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Stryker Corp. holds 4 510(k) clearances for devices named "bone cement". | 4 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Biodynamic Technologies, Inc. holds 3 510(k) clearances for devices named "bone cement". | 3 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
Companies to watch
Depuy Orthopaedics, Inc.
11 FDA 510(k) clearances for devices named "bone cement".
Biomet, Inc.
9 FDA 510(k) clearances for devices named "bone cement".
G21, S.R.L.
4 FDA 510(k) clearances for devices named "bone cement".
Medtronic
4 FDA 510(k) clearances for devices named "bone cement".
Stryker Corp.
4 FDA 510(k) clearances for devices named "bone cement".
Biodynamic Technologies, Inc.
3 FDA 510(k) clearances for devices named "bone cement".
What the full report covers
- 1
Executive summary
The answer on two pages: size, growth and what drives it.
- 2
Market size and outlook
History, the current year and a five-year view with base, low and high cases.
- 3
Segments and regions
Splits by product, buyer and geography across the US, Europe and MEA.
- 4
Company profiles
The main players, how they compete and where they are investing.
- 5
Data and method
Every figure in Excel, with the sources and assumptions behind it.
- 01Executive summary
The answer in one page: size, direction and what moves it - 02Market definition and scope
What is in and out of the European Union market - 03Market size, 2021 to 2025
Historical series and growth rates - 04Outlook to 2031
Base, low and high scenarios with stated assumptions - 05Rules, policy and deadlines
Regulation and programmes that change demand - 06Drivers and barriers
What accelerates or slows adoption, by customer segment - 07Prices, costs and margins
Unit economics where public data allows - 08Competitive landscape
8 to 12 company profiles with recent moves - 09Opportunities and risks
For new entrants, suppliers and investors - 10Method and sources
Every assumption and source, listed
Included with the full report
- PDF report, 40 to 60 pages
- Excel data pack
- Ready-to-use charts
- Method note and assumptions
- Written to order in 5 working days
Frequently asked questions
How big is the EU bone glue market?
There is no single official market total. Eurostat trade data shows the EU imported €524.6 million of goods under CN 30064000 from outside the EU in 2025 and exported €1.03 billion.
Where does the EU import bone glue from?
Liechtenstein was the largest non-EU supplier in 2025. The next largest were Japan, United States from 1995 -> 2000), United Kingdom.
What is the average import price of bone glue in the EU?
Dividing Eurostat import value by weight gives about €416.32 per kilogram for CN 30064000 in 2025.
Which EU countries export the most bone glue?
Germany led EU exports to non-EU countries in 2025, followed by Netherlands, Ireland.
How many bone glue devices are cleared by the FDA?
openFDA lists 112 510(k) clearances for devices named bone cement.
Which companies hold the most FDA clearances for bone glue?
By 510(k) count: Depuy Orthopaedics, Inc., Biomet, Inc., G21, S.R.L., Medtronic.
Sources and method
The figures on this page come from the public sources listed below. Read how we work.
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, partner EXT_EU27_2020, flow import, 2025, VALUE_IN_EUROS 524590100
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, flow import, 2020 VALUE_IN_EUROS 226040884; 2025 VALUE_IN_EUROS 524590100
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, partner EXT_EU27_2020, flow export, 2025, VALUE_IN_EUROS 1027143949
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, partner INT_EU27_2020, flow import, 2025, VALUE_IN_EUROS 876334984
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, partner LI, flow import, 2025, VALUE_IN_EUROS 216170266
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, partner US, flow export, 2025, VALUE_IN_EUROS 329215207
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter EU27_2020, product 30064000, flow import, 2025, VALUE_IN_EUROS 524590100, QUANTITY_IN_100KG 12601
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
DS-045409, reporter DE, product 30064000, partner EXT_EU27_2020, flow export, 2025, VALUE_IN_EUROS 516650046
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
sbs_ovw_act, geo EU27_2020, nace_r2 C2052, indic_sbs ENT_NR, 2023, 480
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
sbs_ovw_act, geo EU27_2020, nace_r2 C2052, indic_sbs NETTUR_MEUR, 2023, 5891
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
sbs_ovw_act, geo EU27_2020, nace_r2 C2052, indic_sbs EMP_NR, 2023, 15518
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 325520, 2025 (2026-11-04)
QCEW 2025 annual, US000, private, NAICS 325520, annual_avg_estabs 779
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 325520, 2025 (2026-11-04)
QCEW 2025 annual, US000, private, NAICS 325520, annual_avg_emplvl 24219
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 325520, 2025 (2026-11-04)
QCEW 2020 annual_avg_emplvl 22304; 2025 annual_avg_emplvl 24219
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 325520, 2025 (2026-11-04)
QCEW 2025 annual, US000, private, NAICS 325520, avg_annual_pay 94437
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances, device_name "bone cement" (2026-11-04)
openFDA device/510k device_name:"bone cement", sum of counts by decision_date = 112
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances, device_name "bone cement" (2026-11-04)
openFDA device/510k decision_date 2021-2025 count = 17
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone cement" (2026-11-04)
applicant.exact "DePuy Orthopaedics, Inc." count 11
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone cement" (2026-11-04)
applicant.exact "Biomet, Inc." count 9
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone cement" (2026-11-04)
applicant.exact "G21, S.R.L." count 4
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone cement" (2026-11-04)
applicant.exact "Medtronic" count 4
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone cement" (2026-11-04)
applicant.exact "Stryker Corp." count 4
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone cement" (2026-11-04)
applicant.exact "Biodynamic Technologies, Inc." count 3
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