63,227 enterprises
The EU had 63,227 enterprises in NACE class C3250 (Manufacture of medical and dental instruments and supplies) in 2023.
Eurostat105.31 EUR billion
EU enterprises in NACE class C3250 had net turnover of €105.31 billion in 2021.
EurostatWhy this market is moving now
- US employment in the core industry shifted +3% since 2020.
What this market covers
Sterile wax applied to cut bone surfaces to stop bleeding during surgery. It is used in orthopedic, spine, heart and neurosurgery.
Typical segments
- Beeswax based bone wax
- Synthetic bone wax
- Absorbable bone hemostats
- Single use bone wax packs
Who buys
- Hospitals
- Surgeons
- Surgical supply distributors
Key figures
Each figure links to the page it came from.
| Figure | Value | Year | Source |
|---|---|---|---|
| The EU had 63,227 enterprises in NACE class C3250 (Manufacture of medical and dental instruments and supplies) in 2023. | 63,227 enterprises | 2023 | Eurostat |
| EU enterprises in NACE class C3250 had net turnover of €105.31 billion in 2021. | 105.31 EUR billion | 2021 | Eurostat |
| NACE class C3250 employed 600,000 people across the EU in 2023. | 600,000 persons employed | 2023 | Eurostat |
| The US had 3,528 private establishments in NAICS 339113 (Surgical appliance and supplies manufacturing) in 2025. | 3,528 establishments | 2025 | U.S. Bureau of Labor Statistics |
| NAICS 339113 employed an average of 105,116 people in US private industry in 2025. | 105,116 jobs | 2025 | U.S. Bureau of Labor Statistics |
| US employment in NAICS 339113 changed by +3% between 2020 (102,053 jobs) and 2025, calculated from BLS figures. | +3 % change | 2025 | U.S. Bureau of Labor Statistics |
| Average annual pay in US NAICS 339113 was $102,311 in 2025. | 102,311 USD per year | 2025 | U.S. Bureau of Labor Statistics |
| The FDA has recorded 10 510(k) clearances for devices named "bone wax". | 10 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Ceremed , Inc. holds 3 510(k) clearances for devices named "bone wax". | 3 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Cp Medical holds 2 510(k) clearances for devices named "bone wax". | 2 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Aesculap, Inc. holds 1 510(k) clearances for devices named "bone wax". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Lukens Corp. holds 1 510(k) clearances for devices named "bone wax". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Phillips Pharmaceuticals, Inc. holds 1 510(k) clearances for devices named "bone wax". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
| Surgical Specialties Corp holds 1 510(k) clearances for devices named "bone wax". | 1 510(k) clearances | 2026 | U.S. Food and Drug Administration (openFDA) |
Companies to watch
Ceremed , Inc.
3 FDA 510(k) clearances for devices named "bone wax".
Cp Medical
2 FDA 510(k) clearances for devices named "bone wax".
Aesculap, Inc.
1 FDA 510(k) clearances for devices named "bone wax".
Lukens Corp.
1 FDA 510(k) clearances for devices named "bone wax".
Phillips Pharmaceuticals, Inc.
1 FDA 510(k) clearances for devices named "bone wax".
Surgical Specialties Corp
1 FDA 510(k) clearances for devices named "bone wax".
What the full report covers
- 1
Executive summary
The answer on two pages: size, growth and what drives it.
- 2
Market size and outlook
History, the current year and a five-year view with base, low and high cases.
- 3
Segments and regions
Splits by product, buyer and geography across the US, Europe and MEA.
- 4
Company profiles
The main players, how they compete and where they are investing.
- 5
Data and method
Every figure in Excel, with the sources and assumptions behind it.
- 01Executive summary
The answer in one page: size, direction and what moves it - 02Market definition and scope
What is in and out of the United States market - 03Market size, 2021 to 2025
Historical series and growth rates - 04Outlook to 2031
Base, low and high scenarios with stated assumptions - 05Rules, policy and deadlines
Regulation and programmes that change demand - 06Drivers and barriers
What accelerates or slows adoption, by customer segment - 07Prices, costs and margins
Unit economics where public data allows - 08Competitive landscape
8 to 12 company profiles with recent moves - 09Opportunities and risks
For new entrants, suppliers and investors - 10Method and sources
Every assumption and source, listed
Included with the full report
- PDF report, 40 to 60 pages
- Excel data pack
- Ready-to-use charts
- Method note and assumptions
- Written to order in 5 working days
Frequently asked questions
How many bone wax devices are cleared by the FDA?
openFDA lists 10 510(k) clearances for devices named bone wax.
Which companies hold the most FDA clearances for bone wax?
By 510(k) count: Ceremed , Inc., Cp Medical, Aesculap, Inc., Lukens Corp..
How many US companies are in the bone wax industry?
BLS counts 3,528 private establishments in NAICS 339113 (Surgical appliance and supplies manufacturing), the closest official industry.
How many EU companies are in the bone wax industry?
Eurostat counts 63,227 enterprises in NACE class C3250 (Manufacture of medical and dental instruments and supplies).
Sources and method
The figures on this page come from the public sources listed below. Read how we work.
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
sbs_ovw_act, geo EU27_2020, nace_r2 C3250, indic_sbs ENT_NR, 2023, 63227
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
sbs_ovw_act, geo EU27_2020, nace_r2 C3250, indic_sbs NETTUR_MEUR, 2021, 105308
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
sbs_ovw_act, geo EU27_2020, nace_r2 C3250, indic_sbs EMP_NR, 2023, 600000
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 339113, 2025 (2026-11-04)
QCEW 2025 annual, US000, private, NAICS 339113, annual_avg_estabs 3528
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 339113, 2025 (2026-11-04)
QCEW 2025 annual, US000, private, NAICS 339113, annual_avg_emplvl 105116
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 339113, 2025 (2026-11-04)
QCEW 2020 annual_avg_emplvl 102053; 2025 annual_avg_emplvl 105116
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 339113, 2025 (2026-11-04)
QCEW 2025 annual, US000, private, NAICS 339113, avg_annual_pay 102311
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances, device_name "bone wax" (2026-11-04)
openFDA device/510k device_name:"bone wax", sum of counts by decision_date = 10
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone wax" (2026-11-04)
applicant.exact "Ceremed , Inc." count 3
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone wax" (2026-11-04)
applicant.exact "Cp Medical" count 2
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone wax" (2026-11-04)
applicant.exact "Aesculap, Inc." count 1
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone wax" (2026-11-04)
applicant.exact "Lukens Corp." count 1
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone wax" (2026-11-04)
applicant.exact "Phillips Pharmaceuticals, Inc." count 1
- U.S. Food and Drug Administration (openFDA): openFDA 510(k) clearances by applicant, device_name "bone wax" (2026-11-04)
applicant.exact "Surgical Specialties Corp" count 1
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