What this market covers
Treatment and prevention of poisoning from botulinum toxin, mainly with antitoxin and supportive intensive care. It also covers diagnostics and surveillance for food borne, wound and infant cases.
Typical segments
- Antitoxin therapy
- Diagnostic testing
- Infant botulism treatment
- Biodefence countermeasures
Source: Eurostat
Why this market is moving now
- Extra-EU import value moved +60% from 2020 to 2025, a direct read on EU demand for sourced supply.
- Supply is concentrated: one country provided a large share of extra-EU imports in 2025.
- US employment in the core industry shifted +23% since 2020.
- Clinical research is active, with studies recruiting now.
Key figures
Each figure names the source it came from. Open the source list below to read the quoted line.
| Figure | Value | Year | Source |
|---|---|---|---|
| The EU imported €8.64 billion of products under CN code 30021200 (Antisera and other blood fractions) from outside the EU in 2025. | 8.64 EUR billion | 2025 | Eurostat |
| Extra-EU imports of CN 30021200 were up 60% in 2025 compared with 2020 (€5.40 billion), calculated from Eurostat values. | +60 % change | 2025 | Eurostat |
| EU exports of CN 30021200 to countries outside the EU were worth €12.99 billion in 2025. | 12.99 EUR billion | 2025 | Eurostat |
| Trade between EU member states in CN 30021200 (intra-EU arrivals) came to €12.51 billion in 2025. | 12.51 EUR billion | 2025 | Eurostat |
| United States was the largest non-EU supplier of CN 30021200 to the EU in 2025, with €6.52 billion, or 75% of extra-EU imports. | 6.52 EUR billion | 2025 | Eurostat |
| EU exports of CN 30021200 to the United States were €4.17 billion in 2025. | 4.17 EUR billion | 2025 | Eurostat |
| The average value of extra-EU imports of CN 30021200 was €277.61 per kilogram in 2025, calculated from Eurostat value and weight. | 277.61 EUR per kg | 2025 | Eurostat |
| Germany was the largest EU exporter of CN 30021200 to non-EU countries in 2025, at €5.10 billion. | 5.10 EUR billion | 2025 | Eurostat |
| The EU had 3,116 enterprises in NACE class C2120 (Manufacture of pharmaceutical preparations) in 2023. | 3,116 enterprises | 2023 | Eurostat |
| EU enterprises in NACE class C2120 had net turnover of €428.65 billion in 2023. | 428.65 EUR billion | 2023 | Eurostat |
| NACE class C2120 employed 600,730 people across the EU in 2023. | 600,730 persons employed | 2023 | Eurostat |
| The US had 830 private establishments in NAICS 325414 (Biological product (except diagnostic) manufacturing) in 2025. | 830 establishments | 2025 | U.S. Bureau of Labor Statistics |
| NAICS 325414 employed an average of 46,853 people in US private industry in 2025. | 46,853 jobs | 2025 | U.S. Bureau of Labor Statistics |
| US employment in NAICS 325414 changed by +23% between 2020 (38,064 jobs) and 2025, calculated from BLS figures. | +23 % change | 2025 | U.S. Bureau of Labor Statistics |
| Average annual pay in US NAICS 325414 was $124,162 in 2025. | 124,162 USD per year | 2025 | U.S. Bureau of Labor Statistics |
| ClinicalTrials.gov lists 24 registered studies for the condition "botulism". | 24 registered studies | 2026 | U.S. National Library of Medicine |
| 1 of those studies were recruiting participants when checked in November 2026. | 1 recruiting studies | 2026 | U.S. National Library of Medicine |
Sources and method
The figures on this page come from the public sources listed below. Read how we work.
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
Quoted lines
- Figure 1
DS-045409, reporter EU27_2020, product 30021200, partner EXT_EU27_2020, flow import, 2025, VALUE_IN_EUROS 8643190927
- Figure 2
DS-045409, reporter EU27_2020, product 30021200, flow import, 2020 VALUE_IN_EUROS 5401238343; 2025 VALUE_IN_EUROS 8643190927
- Figure 3
DS-045409, reporter EU27_2020, product 30021200, partner EXT_EU27_2020, flow export, 2025, VALUE_IN_EUROS 12991722489
- Figure 4
DS-045409, reporter EU27_2020, product 30021200, partner INT_EU27_2020, flow import, 2025, VALUE_IN_EUROS 12508361537
- Figure 5
DS-045409, reporter EU27_2020, product 30021200, partner US, flow import, 2025, VALUE_IN_EUROS 6516963300
- Figure 6
DS-045409, reporter EU27_2020, product 30021200, partner US, flow export, 2025, VALUE_IN_EUROS 4168373985
- Figure 7
DS-045409, reporter EU27_2020, product 30021200, flow import, 2025, VALUE_IN_EUROS 8643190927, QUANTITY_IN_100KG 311345
- Figure 1
- Eurostat: EU trade since 1988 by HS2-4-6 and CN8 (DS-045409) (2026-11-04)
Quoted lines
- Figure 8
DS-045409, reporter DE, product 30021200, partner EXT_EU27_2020, flow export, 2025, VALUE_IN_EUROS 5104052530
- Figure 8
- Eurostat: Enterprises by detailed NACE Rev. 2 activity and special aggregates (sbs_ovw_act) (2026-11-04)
Quoted lines
- Figure 9
sbs_ovw_act, geo EU27_2020, nace_r2 C2120, indic_sbs ENT_NR, 2023, 3116
- Figure 10
sbs_ovw_act, geo EU27_2020, nace_r2 C2120, indic_sbs NETTUR_MEUR, 2023, 428651
- Figure 11
sbs_ovw_act, geo EU27_2020, nace_r2 C2120, indic_sbs EMP_NR, 2023, 600730
- Figure 9
- U.S. Bureau of Labor Statistics: QCEW annual averages, NAICS 325414, 2025 (2026-11-04)
Quoted lines
- Figure 12
QCEW 2025 annual, US000, private, NAICS 325414, annual_avg_estabs 830
- Figure 13
QCEW 2025 annual, US000, private, NAICS 325414, annual_avg_emplvl 46853
- Figure 14
QCEW 2020 annual_avg_emplvl 38064; 2025 annual_avg_emplvl 46853
- Figure 15
QCEW 2025 annual, US000, private, NAICS 325414, avg_annual_pay 124162
- Figure 12
- U.S. National Library of Medicine: ClinicalTrials.gov API v2, condition "botulism" (2026-11-04)
Quoted lines
- Figure 16
query.cond=botulism totalCount 24
- Figure 16
- U.S. National Library of Medicine: ClinicalTrials.gov API v2, condition "botulism", status recruiting (2026-11-04)
Quoted lines
- Figure 17
filter.overallStatus=RECRUITING totalCount 1
- Figure 17
Buyers and suppliers
Who buys
- Hospitals
- Public health agencies
- Defence agencies
Large non-EU suppliers to the EU
What the full report covers
- 01Executive summary
The answer in one page: size, direction and what moves it - 02Market definition and scope
What is in and out of the European Union market - 03Market size, 2021 to 2025
Historical series and growth rates - 04Outlook to 2031
Base, low and high scenarios with stated assumptions - 05Rules, policy and deadlines
Regulation and programmes that change demand - 06Drivers and barriers
What accelerates or slows adoption, by customer segment - 07Prices, costs and margins
Unit economics where public data allows - 08Competitive landscape
8 to 12 company profiles with recent moves - 09Opportunities and risks
For new entrants, suppliers and investors - 10Method and sources
Every assumption and source, listed
Included with the full report
- PDF report, 40 to 60 pages
- Excel data pack
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- Method note and assumptions
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Frequently asked questions
How big is the EU botulism market?
There is no single official market total. Eurostat trade data shows the EU imported €8.64 billion of goods under CN 30021200 from outside the EU in 2025 and exported €12.99 billion.
Where does the EU import botulism from?
United States was the largest non-EU supplier in 2025. Other large suppliers included Switzerland, United Kingdom, Australia.
What is the average import price of botulism in the EU?
Dividing Eurostat import value by weight gives about €277.61 per kilogram for CN 30021200 in 2025.
Which EU countries export the most botulism?
Germany led EU exports to non-EU countries in 2025, followed by Austria, Ireland.
How many clinical trials study botulism?
ClinicalTrials.gov lists 24 registered studies.
How many US companies are in the botulism industry?
BLS counts 830 private establishments in NAICS 325414 (Biological product (except diagnostic) manufacturing), the closest official industry.
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